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Isobaric protein and peptide quantification: perspectives and issues

โœ Scribed by Treumann, Achim; Thiede, Bernd


Book ID
115464238
Publisher
Expert Reviews
Year
2010
Tongue
English
Weight
308 KB
Volume
7
Category
Article
ISSN
1478-9450

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Isobaric tagging, via TMT or iTRAQ, is widely used in quantitative proteomics. To date, tandem mass spectrometric analysis of isobarically-labeled peptides with hybrid ion trap-orbitrap (LTQ-OT) instruments has been mainly carried out with higher-energy C-trap dissociation (HCD) or pulsed q dissocia

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