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Islet1, a transcription factor, promotes cardiac differentiation

✍ Scribed by Anthony J. White; Satoshi Matsushita; Tarun Chakravarty; James S. Forrester; Eduardo Marbán; Raj Makkar

Book ID
119256745
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
64 KB
Volume
18
Category
Article
ISSN
1443-9506

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## Abstract In this study, the functional role of INSM1 is examined with an AR42J acinar cell model for trans‐differentiation into insulin‐positive cells. Islet transcription factors (ITFs: INSM1, Pdx‐1, and NeuroD1) are over‐expressed in AR42J cells using adenoviral vectors. Addition of Ad‐INSM1 a