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Islet-brain 1/c-Jun N-terminal kinase interacting protein-1 (IB1/JIP-1) promoter variant is associated with Alzheimer's disease

✍ Scribed by Helbecque, N; Abderrhamani, A; Meylan, L; Riederer, B; Mooser, V; Miklossy, J; Delplanque, J; Boutin, P; Nicod, P; Haefliger, J A

Book ID: 110059647
Publisher: Nature Publishing Group
Year: 2003
Tongue: English
Weight: 77 KB
Volume: 8
Category: Article
ISSN: 1359-4184
DOI: 10.1038/sj.mp.4001342

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## Abstract Islet‐brain 1 [IB1; also termed c‐Jun N‐terminal kinase (JNK)‐interacting protein 1 (__JIP‐1__] is involved in the apoptotic signaling cascade of JNK and functions as a scaffold protein. It organizes several MAP kinases and the microtubule‐transport motor protein kinesin and relates to