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Ischemic Tolerance: The Mechanisms of Neuroprotective Strategy

✍ Scribed by Jan Lehotský; Jozef Burda; Viera DanielisovÁ; Miroslav Gottlieb; Peter Kaplán; Beata Saniová


Publisher
Wiley (John Wiley & Sons)
Year
2009
Tongue
English
Weight
242 KB
Volume
292
Category
Article
ISSN
1932-8486

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The four most prominent hypotheses on the cellular processes leading to hypoxic-ischemic neuronal damage or death are (1) the lactacidosis hypothesis, (2) the calcium overload hypothesis, (3) the excitotoxic hypothesis, and (4) the oxygen-free radical hypothesis. The authors comment on the evidence