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Ischaemic Tolerance in Aged Mouse Myocardium: The Role of Adenosine and Effects of A1 Adenosine Receptor Overexpression

✍ Scribed by John P. Headrick; Laura Willems; Kevin J. Ashton; Kirsten Holmgren; Jason Peart; G. Paul Matherne


Book ID
110112261
Publisher
Cambridge University Press
Year
2003
Tongue
English
Weight
473 KB
Volume
549
Category
Article
ISSN
0022-3751

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The advent of transgenic techniques provides a unique opportunity to study adenosine receptor-mediated cardioprotection. Transgenic A 1 receptor overexpression increases myocardial protection without impairing intrinsic function, but at the expense of resting bradycardia and a blunted response to ca