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Isatoic Anhydride. IV. Reactions with Various Nucleophiles

โœ Scribed by STAIGER, ROGER P.; MILLER, EMERY B.


Book ID
115517561
Publisher
American Chemical Society
Year
1959
Tongue
English
Weight
691 KB
Volume
24
Category
Article
ISSN
0022-3263

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A ring opening and dimerization reaction of benzoyleneurea (1) or isatoic anhydride (2) with thionyl chloride in DMF (Vilsmeier reagent), to yield N,N-dimethyl-2-(4-oxo-3(4H)-quinazolinyl)benzamide (4), is described.