𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Is β2-microglobulin required for MHC class I heavy chain expression?

✍ Scribed by W. Lee Maloy; John E. Coligan


Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
186 KB
Volume
6
Category
Article
ISSN
0167-5699

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Stable expression of MHC class I heavy c
✍ Marcel van Lith; Marieke van Ham; Jacques Neefjes 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 180 KB

## Abstract Major histocompatibility complex (MHC) class I and II molecules present antigenic fragments to the immune system. MHC‐like chaperones, like HLA‐DM, HLA‐DO and tapasin support peptide loading. HLA class I heavy chains require association with β2‐microglobulin and peptide for endoplasmic

β2 -Microglobulin-deficient NK cells sho
✍ Petter Höglund; Rickard Glas; Carine Ménard; Anna Kåse; Maria H. Johansson; Lars 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 145 KB

Mice lacking beta2-microglobulin (beta2m- mice) express greatly reduced levels of MHC class I molecules, and cells from beta2m- mice are therefore highly sensitive to NK cells. However, NK cells from beta2m- mice fail to kill beta2m- normal cells, showing that they are self tolerant. In a first atte