Is True Follicular Thyroid Carcinoma Much Rarer Than Previously Reported?
✍ Scribed by Kristen J. Otto; Jacqueline S.C. Lam; Christina MacMillan; Jeremy L. Freeman
- Book ID
- 102448047
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 165 KB
- Volume
- 119
- Category
- Article
- ISSN
- 0023-852X
No coin nor oath required. For personal study only.
✦ Synopsis
Objective: Follicular thyroid carcinomas have been traditionally reported to represent 10-15% of all thyroid malignancies, while papillary cancers have been reported as approximately 80%. The problem with these figures is that they fail to account for changing diagnostic criteria and incidence patterns among papillary cancers. A review of multiple large, long-term, cross-sectional cancer registries ( † NCD, † † SEER) demonstrates that the incidence of papillary thyroid cancer has risen 2.4-fold over the last 30 years. Also, the histologic criteria required for making the diagnosis of papillary cancer, and differentiating the follicular variant of papillary from true follicular carcinoma have undergone a tremendous evolution. We aim to document the true proportion of follicular thyroid cancers in a cohort from a high-volume academic head and neck endocrine surgery practice.