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Is there still a need for candidate gene approaches in the era of genome-wide association studies?

✍ Scribed by Stefan Wilkening; Bowang Chen; Justo Lorenzo Bermejo; Federico Canzian


Book ID
116981842
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
462 KB
Volume
93
Category
Article
ISSN
0888-7543

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## Abstract The large number of markers considered in a genome‐wide association study (GWAS) has resulted in a simplification of analyses conducted. Most studies are analyzed one marker at a time using simple tests like the trend test. Methods that account for the special features of genetic associ