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Is there an association of regulatory region polymorphism in the alpha-1-antichymotrypsin gene with sporadic Alzheimer’s disease in the northern Han-Chinese population?

✍ Scribed by Guran Yu; Jianping Jia


Book ID
116675417
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
133 KB
Volume
17
Category
Article
ISSN
0967-5868

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Polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE) and DNA sequencing were employed to screen the coding region of the alpha-antichymotrypsin (AACT) gene in Han-Chinese population for polymorphism possibly associated with Alzheimer's disease (AD). Consequently, seven polymo