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Is there a role for recombinant insulin-like growth factor-I in the treatment of idiopathic short stature?

✍ Scribed by Arlan L Rosenbloom


Book ID
117299725
Publisher
The Lancet
Year
2006
Tongue
English
Weight
69 KB
Volume
368
Category
Article
ISSN
0140-6736

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✍ Dunger, D.B; Acerini, C.L. πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 189 KB πŸ‘ 2 views

The structure of IGF-I is similar to that of insulin, having 43 % sequence homology with human proinsulin. Both peptides can induce metabolic and mitogenic effects through their own specific receptors, which also share many structural and functional similarities. Primarily involved in the regulation