Is there a lung-cancer susceptibility gene?
β Scribed by M.J. Renan
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- French
- Weight
- 73 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Glutathione S-transferases (GSTs) are known to take part in detoxification of many potentially carcinogenic compounds. Therefore, polymorphisms of the GST genes have been considered as potentially important modifiers of individual risk of environmentally induced cancers. The association between lack
## Background: Hexavalent chromium has been extensively investigated regarding its mutagenicity and carcinogenicity; however, its mechanism for initiating and enhancing the development of lung cancer is still obscure. biomarkers of exposure, effect or susceptibility are required for risk assessment
Among the major regulators of the G 1 restriction point are cyclin D1 and the retinoblastoma gene product (RB). In non-small cell lung cancer (NSCLC), the cyclin D1 gene is amplified/over-expressed in almost 50% of cases, and RB is inactivated in 6-32% of cases. It is of interest to evaluate concurr
## Abstract ## __Objective__ The __UCHLβ1__ gene is widely cited as a susceptibility factor for sporadic Parkinson's disease (PD). The strongest evidence comes from a metaβanalysis of small studies that reported the S18Y polymorphism as protective against PD, after pooling studies of white and Asi
The Swedish Family-Cancer Database was used to analyze familial relationships in mothers and daughters in invasive and in situ cervical cancers from years 1958-1994, including a total of 125,000 in situ and 14,000 invasive cancers. In situ cancers were diagnosed on average 10 years earlier than inva