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Is There a “Critical Period” for Intervention in Posttraumatic Epilepsy?

✍ Scribed by F. Edward Dudek; Suzanne Clark


Book ID
109138760
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
44 KB
Volume
4
Category
Article
ISSN
1535-7597

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A critical period for prevention of post
✍ Kevin D. Graber; David A. Prince 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 348 KB

Penetrating cortical trauma frequently results in delayed development of epilepsy. In the rat undercut model of neocortical posttraumatic hyperexcitability, suppression of neuronal activity by exposing the injured cortex to tetrodotoxin (TTX) in vivo for approximately 2 weeks prevents the expression