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Is the primary event in radiation-induced chronic myelogenous leukemia the induction of the t(9;22) translocation?

✍ Scribed by M. Holmberg


Book ID
113239657
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
341 KB
Volume
16
Category
Article
ISSN
0145-2126

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Breakpoints of variant 9;22 translocatio
✍ Andrew M. Fisher; Paul Strike; Claire Scott; Anthony V. Moorman πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 211 KB

## Abstract From 5% to 10% of 9;22 translocations in chronic myeloid leukemia (CML) are reported to occur in variant form, that is, with the involvement of other regions of the genome in 3‐way or more rearrangements. The literature indicates that the alternative breakpoints are not distributed rand