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Is the pathway of energy metabolism modified in advanced cirrhosis?

✍ Scribed by Ganapathy-Kanniappan, Shanmugasundaram; Karthikeyan, Swathi; Geschwind, Jean-Francois; Mezey, Esteban


Book ID
122168979
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
178 KB
Volume
61
Category
Article
ISSN
0168-8278

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Aromatic hydroxylation is a major metabo
✍ Erika Pfeiffer; Andreas Hildebrand; Georg Damm; Andreas Rapp; Benedikt Cramer; H πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 869 KB

## Abstract Zearalenone (ZEN) is a common mycotoxin, for which only reductive metabolites have been identified so far. We now report that ZEN is extensively monohydroxylated by microsomes from human liver __in vitro__. Two of the major oxidative metabolites arise through aromatic hydroxylation and