𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Is the JAK2V617F mutation detectable in healthy volunteers?

✍ Scribed by Christophe Martinaud; Patrick Brisou; Marie-Joelle Mozziconacci

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
705 KB
Volume
85
Category
Article
ISSN
0361-8609

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

The V617F JAK2 mutation and the myelopro
The V617F JAK2 mutation and the myeloproliferative disorders
✍ Melanie J Percy; Mary Frances McMullin πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 70 KB

## Abstract The discovery this year of a single mutation in the Janus Kinase (__JAK__)‐2 gene in a high percentage of cases of polycythaemia vera (PV), essential thrombocythaemia (ET) and myelofibrosis suggests that it maybe the underlying molecular mechanism for these disorders. Different approach

P124 The prevalence of JAK2 V617F mutati
P124 The prevalence of JAK2 V617F mutation in myelodysplastic syndrome
✍ M. Radič Antolic; R. Zadro; P. Rončevič; S. BaΕ‘ič Kinda; B. Labar πŸ“‚ Article πŸ“… 2007 πŸ› Elsevier Science 🌐 English βš– 46 KB

reductase enzyme mutation, 5Gdel1G of gen PAI-1) and hyperhomocysteinaemia up to 24 mcmol/L were also discovered. Patient received interferon-alpha, hydroxyurea, acetylsalicylic acid, sulodexide, vitamin therapy B6, B12 with positive effect. We observed disappearance of ascites, reduction of the siz

Fully automated and super-rapid system f
Fully automated and super-rapid system for the detection of JAK2V617F mutation
✍ Ruriko Tanaka; Junya Kuroda; William Stevenson; Eishi Ashihara; Takayuki Ishikaw πŸ“‚ Article πŸ“… 2008 πŸ› Elsevier Science 🌐 English βš– 664 KB

JAK2V617F is a common mutation in chronic myeloproliferative diseases (CMPDs). We have developed a system utilizing JAK2V617Fspecific guanine quenching probe (QP-system) to detect JAK2V617F. With QP-system, results can be obtained from 100 l of blood within 90 min. We compared QP-system with direct