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Is Ro15-1788 a partial agonist at benzodiazepine receptors?

✍ Scribed by Sandra V. Vellucci; Roy A. Webster


Book ID
115877812
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
404 KB
Volume
90
Category
Article
ISSN
0014-2999

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ZK 91296, a partial agonist at benzodiaz
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ZK 91296 (ethyl 5-benzyloxy-4-methoxymethyl-ficarboline-3-carboxylate) is a potent and selective ligand for benzodiazepine (BZ) receptors. Biochemical investigations indicate that ZK 91296 may be a partial agonist at BZ receptors. Such partial agonism may explain to some extent why ZK 91296 needs hi