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Is plasma cell-free DNA really a useful marker for diagnosis and treatment of trauma patients?

✍ Scribed by Ren, Biqiong; Liu, Fengwei; Xu, Fei; He, Junyu; Zhu, Haowen; Zou, Guoying


Book ID
125448996
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
332 KB
Volume
424
Category
Article
ISSN
0009-8981

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## Abstract Abnormal DNA methylation is a feature of most types of cancer, which is reflected in cell‐free circulating DNA in plasma. It is, however, unknown whether surgical removal of the tumor and subsequent therapy induces changes in plasma DNA methylation, which can be used to monitor treatmen