𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Is NF-κB a good target for cancer therapy? Hopes and pitfalls

✍ Scribed by Baud, Véronique; Karin, Michael

Book ID
109950722
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
454 KB
Volume
8
Category
Article
ISSN
1474-1776

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

NF-κB in liver diseases: a target for dr
NF-κB in liver diseases: a target for drug therapy
✍ Pablo Muriel 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 231 KB

## Abstract There are five nuclear factor‐__κ__B (NF‐__κ__B) transcription factors with important roles in innate immunity, liver inflammation, fibrosis and apoptosis prevention. Several inhibitors of NF‐__κ__B, like caffeic acid, captopril, curcumin, pyrrolidine dithiocarbamate, resveratrol, silym

TAp63 is a transcriptional target of NF-
TAp63 is a transcriptional target of NF-κB
✍ Junfeng Wu; Johann Bergholz; Jinin Lu; Gail E. Sonenshein; Zhi-Xiong Jim Xiao 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 282 KB

## Abstract The p53 homologue p63 encodes multiple protein isoforms either with (TA) or without (ΔN) the N‐terminal transactivation domain. Accumulating evidence indicates that TAp63 plays an important role in various biological processes, including cell proliferation, differentiation, and apoptosi

Blocking anti-apoptosis as a strategy fo
Blocking anti-apoptosis as a strategy for cancer chemotherapy: NF-κB as a target
✍ N.R. Monks; D.K. Biswas; A.B. Pardee 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 71 KB

## Abstract Critical processes underlying cancers must be better understood to develop strategies for treatment and prevention. A chemotherapeutic strategy is proposed that is based upon re‐establishment, with a drug, of nullified programmed cell death (apoptosis) in cancer cells, which to survive