Abetalipoproteinemia (ABL) is an extremely rare autosomal recessive disorder, which is characterized by defective assembly and secretion of plasma apolipoprotein (apo) Bcontaining lipoproteins. ABL results from mutations in the gene encoding the microsomal triglyceride transfer protein (MTP). We seq
Is microsomal triglyceride transfer protein the missing link in abetalipoproteinemia?
โ Scribed by Robert L. Hamilton; Richard J. Havel
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 574 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Nonalcoholic fatty liver disease (NAFLD) is emerging as an independent cardiovascular risk factor, but mechanism(s) linking fatty liver to atherosclerosis are unknown. Microsomal triglyceride transfer protein (MTP) -493 G/T polymorphism modulates circulating lipid and lipoprotein levels in different
## Communicated by David S. Rosenblatt The microsomal triglyceride transfer protein (MTTP) is required for the assembly and secretion of apolipoprotein B (apoB)-containing lipoproteins from the intestine and liver. According to this function, polymorphic sites in the MTTP gene showed associations