Is measurement of IgM and IgA rheumatoid factors (RF) in juvenile rheumatoid arthritis clinically useful?
β Scribed by Rosa A. Ferreira; Carlos H. M. Silva; Deise A. O. Silva; Monica C. Sopelete; Maria H. B. Kiss; Jose R. Mineo; Virginia P. L. Ferriani
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 270 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0172-8172
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π SIMILAR VOLUMES
## Abstract Sera from 10 patients with juvenile arthritis (JA), 2 seropositive and 8 with hidden rheumatoid factor (RF), were subjected to affinity chromatography on a rabbit antiβhuman IgM column. Material retained by the column was eluted sequentially by 1__M__ NH~3~ and 0.1__M__ glycineβHCl buff
Eleven patients with active rheumatoid arthritis were monitored prospectively while receiving up to 1 gm of gold sodium thiomalate. There was a significant decrease in serum and synovial fluid IgG, IgA, and IgM rheumatoid factor (RF) levels over the period of study. Comparison of changes in serum RF