An osteopontin (SPP1) polymorphism is as
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A.C. Forton; M.A. Petri; D. Goldman; K.E. Sullivan
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Article
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2002
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John Wiley and Sons
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English
β 125 KB
Osteopontin (SPP1) is a soluble ligand with pleomorphic immunologic activities including activation of macrophage chemotaxis, promotion of Th1 responses, and activation of B1 B cells. It has been implicated in the development of murine lupus and is overexpressed in humans with systemic lupus erythem