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Is HIF-1α a pro- or an anti-apoptotic protein?

✍ Scribed by Jean-Pascal Piret; Denis Mottet; Martine Raes; Carine Michiels


Book ID
113993148
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
113 KB
Volume
64
Category
Article
ISSN
0006-2952

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## Abstract Hypoxia‐inducible factor‐1α (HIF‐1α) and myeloid cell leukemia‐1 (Mcl‐1) proteins have been shown to regulate apoptosis in some cell systems but have not been studied in this context in airway epithelium. Using a model of anoxia/reoxygenation (A/R), the present study employed RNA interf