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Is glutamine essential for the maintenance of intestinal function? A study in the isolated perfused rat small intestine

✍ Scribed by M. Plauth; A. Raible; D. Vieillard-Baron; D. Bauder-Groß; F. Hartmann

Book ID
106060552
Publisher
Springer
Year
1999
Tongue
English
Weight
373 KB
Volume
14
Category
Article
ISSN
0179-1958

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LY354740 is a potent mGlu2/3 agonist with a limited oral bioavailability. Its alanyl prodrug, LY544344, showed high affinity to the intestinal peptide transporter PEPT1, and improved the oral bioavailability of LY354740 in various animal models. The aim of the present study was to investigate the me