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Is Gilbert Syndrome a new risk factor for breast cancer?

✍ Scribed by Rafael Haddad Astolfi; Diogo Diniz Gomes Bugano; Alice Aparecida Rodrigues Ferreira Francisco; Marcelo Moreira Tavares de Souza; Suzane Kioko Ono-Nita; Edmund Chada Baracat

Book ID
116745961
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
401 KB
Volume
77
Category
Article
ISSN
0306-9877

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## Abstract Genetic risk factors for male breast cancer (MBC) are poorly understood. High penetrance genes such as BRCA1 or BRCA2 account for only a small proportion of the disease. A 1100delC mutation in CHEK2 (previously known as CHK2), a cell‐cycle checkpoint kinase, has been implicated in predi