Is epinephrine administration from a sublingual tablet feasible for the out-of-hospital first aid treatment of anaphylaxis? Absorption studies in an animal model

Is epinephrine administration by subling

Is epinephrine administration by sublingual tablet feasible for the first-aid treatment of anaphylaxis? A proof-of-concept study

✍ Xiaochen Gu; Keith J. Simons; F. Estelle R. Simons 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 60 KB

## Purpose: In order to explore the feasibility of sublingual administration of epinephrine tablets as a non-invasive first-aid treatment for anaphylaxis, we studied epinephrine absorption from this dosage form in an animal model. ## Methods: In a prospective, randomized, four-way crossover study