Evolution of the initial ''three-point attachment model'' resulted in the understanding that an interaction in at least three configuration-dependent points is needed for a chiral selector to recognize entantiomers. Thermodynamic enantioselectivity of this interaction can result in chiral discrimina
β¦ LIBER β¦
Is chiral recognition a three-point process?
β Scribed by Tristan D. Booth; Daphne Wahnon; Irving W. Wainer
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 139 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0899-0042
No coin nor oath required. For personal study only.
β¦ Synopsis
In 1858, Pasteur reported that the dextro form of ammonium tartrate was more rapidly destroyed by the mold Penicillium glaucum than the levo isomer. 1 This was the initial observation of the biological differences between enantiomorphs and led Pasteur to the recognition of the role stereochemistry plays in the basic mechanisms of life.
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