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Is Capecitabine Safe in Patients with Gastrointestinal Cancer and Dihydropyrimidine Dehydrogenase Deficiency?

✍ Scribed by M. Wasif Saif; Robert Diasio


Book ID
119935029
Publisher
CIG Media Group, LP.
Year
2006
Tongue
English
Weight
84 KB
Volume
5
Category
Article
ISSN
1533-0028

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## Abstract ## Purpose To identify if thymidine phosphorylase (TP), dihydropyrimidine dehydrogenase (DPD), and ratio TP/DPD levels in tumor tissues are potential predictive factors for response to combined preoperative chemoradiation with capecitabine, in patients with locally advanced rectal canc