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Is bortezomib, a proteasome inhibitor, effective in treating cancer-associated weight loss? Preliminary results from the North Central Cancer Treatment Group

✍ Scribed by Aminah Jatoi; Steven R. Alberts; Nathan Foster; Roscoe Morton; Patrick Burch; Margaret Block; Phuong L. Nguyen; John Kugler

Book ID
106173453
Publisher
Springer-Verlag
Year
2005
Tongue
English
Weight
99 KB
Volume
13
Category
Article
ISSN
0941-4355

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✍ Aminah Jatoi; Shaker R. Dakhil; Phuong L. Nguyen; Jeff A. Sloan; John W. Kugler; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 142 KB

## Abstract ## BACKGROUND. Tumor necrosis factor‐α (TNF‐α) is a putative mediator of the cancer anorexia/weight loss syndrome. The current study was designed to determine whether etanercept (a dimeric fusion protein consisting of the extracellular ligand‐binding portion of the human 75‐kilodalton