✦ LIBER ✦
Is androgen substitution necessary in hypogonadal patients when they are treated with chemotherapy for malignant diseases?
✍ Scribed by Pavlidis, Nicholas ;Nikolaou, Nikitas ;Tolis, Christos ;Orfanos, Stylianos ;Tolis, George
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 368 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0098-1532
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✦ Synopsis
A patient with hypogonadotropic hypogonadism owing to endogenous gonadotropin releasing hormone deficiency, who developed Hodgkin's disease is described. Chemotherapy administration caused prolonged and life-threatening myelosuppression; androgen substitution seemed to reverse bone marrow function and to maintain normal peripheral blood counts. Whether or not androgens are a necessary substitution in hypogonadal patients suffering from cancer and undergoing chemotherapy is discussed.