gp49B1 deficiency is associated with inc
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Joseph S. Zhou; Daniel S. Friend; David M. Lee; Lin Li; K. Frank Austen; Howard
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Article
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2005
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John Wiley and Sons
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English
⚖ 366 KB
## Abstract Mice with a disrupted gp49B gene, which encodes gp49B1 that is expressed on certain hematopoietic cells and has two immunoreceptor tyrosine‐based inhibitory motifs (ITIM), exhibit augmented FcϵRI‐initiated mast cell degranulation and resultant tissue edema. gp49B1‐deficient (__gp49B^–/–