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Irritable bowel syndrome: A test of the colonic hyperalgesia hypothesis

✍ Scribed by Paul Latimer; Dugal Campbell; Margaret Latimer; Sushil Sarna; Ed Daniel; William Waterfall

Publisher
Springer
Year
1979
Tongue
English
Weight
581 KB
Volume
2
Category
Article
ISSN
0160-7715

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## Abstract ## Objective To assess the efficacy of duloxetine for irritable bowel syndrome (IBS). ## Methods We conducted an open‐label 12‐week trial of duloxetine 60 mg daily in 15 patients with IBS without concurrent major depressive disorder. The primary outcome measure was average abdominal