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Irreversible inhibition of S-adenosylmethionine decarboxylase of trypanosoma bru cei bru cei by S-adenosylmethionine analogues

✍ Scribed by Babu L. Tekwani; Cyrus J. Bacchi; John A. Secrist III; Anthony E. Pegg


Book ID
115782643
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
871 KB
Volume
44
Category
Article
ISSN
0006-2952

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Inhibition of ornithine decarboxylase an
✍ Rentala Madhubala; Anthony E. Pegg πŸ“‚ Article πŸ“… 1992 πŸ› Springer 🌐 English βš– 374 KB

Oligodeoxynucleotides 18 nucleotides in length having sequences complementary to regions spanning the initiation codon regions of ornithine decarboxylase or S-adenosylmethionine decarboxylase mRNAs were tested for their ability to inhibit translation of these mRNAs. In reticulocyte lysates, a strong