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Irreversible enzyme inhibitors. CXXXIX. p-(4,6-Diamino-1,2-dihydro-2,2-dimethyl-s-triazin-1-yl)phenylpropionylsulfanilyl fluoride, an active-site-directed irreversible inhibitor of dihydrofolic reductase. 6. Effects of substitution on the propionamide bridge on isozyme specificity

✍ Scribed by Baker, Bernard Randall; Lourens, Gerhardus J.

Book ID: 127010243
Publisher: American Chemical Society
Year: 1969
Tongue: English
Weight: 284 KB
Volume: 12
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm00301a024

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📜 SIMILAR VOLUMES

Irreversible enzyme inhibitors. CXXVIII.

Irreversible enzyme inhibitors. CXXVIII. p-(4,6-Diamino-1,2-dihydro-2,2-dimethyl-s-triazin-l-yl)phenylpropionylsulfanilyl fluoride, an active site-directed irreversible inhibitor of dihydrofolic reductase. 4. Effects of substitution on the propionamide bridge on isozyme specificity

✍ Baker, B. R.; Lourens, Gerhardus J. 📂 Article 📅 1968 🏛 American Chemical Society 🌐 English ⚖ 735 KB

Irreversible enzyme inhibitors. CXXVII.

Irreversible enzyme inhibitors. CXXVII. p-(2,6-Diamino-1,2-dihydro-2,2-dimethyl-s-triazin-l-yl)phenylpropionylsulfanilyl fluoride, an active site-directed irreversible inhibitor of dihydrofolic reductase. 3. Effects of modification of the propionamide bridge on isozyme specificity

✍ Baker, B. R.; Lourens, Gerhardus J. 📂 Article 📅 1968 🏛 American Chemical Society 🌐 English ⚖ 852 KB

Irreversible enzyme inhibitors. CXXIX. p

Irreversible enzyme inhibitors. CXXIX. p-(4,6-Diamino-1,2-dihydro-2,2-dimethyl-s-triazine-l-yl)phenylpropionylsulfanilyl fluoride, an active site-directed irreversible inhibitor of dihydrofolic reductase. 5. Effects of substitution on the benzenesulfonyl fluoride moiety on isozyme specificity

✍ Baker, B. R.; Lourens, Gerhardus J. 📂 Article 📅 1968 🏛 American Chemical Society 🌐 English ⚖ 664 KB

Irreversible enzyme inhibitors. CLIX. Ef

Irreversible enzyme inhibitors. CLIX. Effect of substitution on transport and isozyme specificity of p-(4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazin-1-yl)-o-chlorophenoxyacetamido-benzenesulfonyl fluoride, an active-site-directed irreversible inhibitor of dihydrofolic reductase

✍ Baker, Bernard Randall; Ashton, Wallace T. 📂 Article 📅 1969 🏛 American Chemical Society 🌐 English ⚖ 444 KB

Irreversible enzyme inhibitors. CLXXVII.

Irreversible enzyme inhibitors. CLXXVII. Active-site-directed irreversible inhibitors of dihydrofolate reductase derived from 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(phenylalkylphenyl)-s-triazines. II

✍ Baker, Bernard Randall; Vermeulen, Nicolaas M. J. 📂 Article 📅 1970 🏛 American Chemical Society 🌐 English ⚖ 662 KB

Irreversible enzyme inhibitors. CLXXIV.

Irreversible enzyme inhibitors. CLXXIV. Metabolism of 4-[p-(4,6-diamino-1,2-dihydro-2,2-dimethyl-s-triazin-1-yl)hydrocinnamido]-o-toluenesulfonyl fluoride (NSC-113423), and active-site-directed irreversible inhibitor of dihydrofolic reductase

✍ Baker, Bernard Randall; Ryan, Adrian J.; Vermeulen, Nicolaas M. J. 📂 Article 📅 1970 🏛 American Chemical Society 🌐 English ⚖ 356 KB