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Irreversible binding of chloramphenicol analogues to E. coli ribosomes

✍ Scribed by R. Bald; V.A. Erdmann; O. Pongs


Book ID
115903162
Publisher
Elsevier Science
Year
1972
Tongue
English
Weight
372 KB
Volume
28
Category
Article
ISSN
0014-5793

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## Abstract Structure‐activity relationships have been discussed for inhibition of [^14^C] erythromycin binding to __Escherichia coli__ ribosomes by leucomycin and its acyl derivatives in the light of the Fujita‐Ban __de novo__ model. The group contributions of various substituents show that acylat