Irradiation crosslinking of the polytetrapeptide of elastin and compounding to dacron to produce a potential prosthetic material with elasticity and strength
✍ Scribed by Urry, D. W. ;Harris, R. D. ;Long, M. M.
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 420 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0021-9304
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✦ Synopsis
The poly(tetra peptide), H-(L . Val1-L . Pro2-Gly3-Gly4)n-L . Val-OMe, which is a recurring sequence in tropoelastin the precursor protein of the elastic fiber, has been irradiation crosslinked to produce an elastomeric material with limited strength. When a material such as a Dacron fabric is impregnated by the coacervate phase of the poly(tetrapeptide) prior to irradiation crosslinking at 50 Mrad, the crosslinked product exhibits stress-strain curves with good elastomeric properties and high strength. In addition to the stress-strain curves, the material is characterized by scanning electron microscopy.