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Iron/Tetramethylethylenediamine-Catalyzed Ambient-Temperature Coupling of Alkyl Grignard Reagents and Aryl Chlorides

✍ Scribed by Rushworth, Philip J.; Hulcoop, David G.; Fox, David J.


Book ID
121220037
Publisher
American Chemical Society
Year
2013
Tongue
English
Weight
322 KB
Volume
78
Category
Article
ISSN
0022-3263

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Low Temperature Studies of Iron-Catalyze
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## Abstract The title reaction has been studied under low temperature conditions. Coupling with active substrates can be done even at dry ice temperature. Initial rate studies at βˆ’25 °C indicate that high concentrations of any reagent can lead to either complete or partial catalyst deactivation. Un