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Ironing out the cryptic intestinal defect in hereditary hemochromatosis

✍ Scribed by Stephen D. Zucker

Book ID
119758369
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
58 KB
Volume
128
Category
Article
ISSN
0016-5085

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Under normal conditions, iron is taken up by the cells through the transferrin-mediated pathway. However, in hereditary hemochromatosis, a common iron-overloading disorder associated with mutations in the HFE gene, iron in plasma exceeds transferrin-binding capacity, and non-transferrin-bound iron (