Two remarkable features of many siderophores produced by oceanic bacteria are the prevalence of an β£-hydroxy-carboxylic acid functionality either in the form of the amino acid β€-hydroxy aspartic acid or in the form of citric acid, as well as the predominance of amphiphilic siderophores. This review
β¦ LIBER β¦
Iron(III)-Templated Macrolactonization of Trihydroxamate Siderophores
β Scribed by Wencewicz, Timothy A.; Oliver, Allen G.; Miller, Marvin J.
- Book ID
- 120239625
- Publisher
- American Chemical Society
- Year
- 2012
- Tongue
- English
- Weight
- 949 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1523-7060
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We present here the physicochemical and biochemical properties of NBD-DFO, the 7-nitrobenz-2-oxa-1,3-diazole (NBD) derivative of the siderophore, desferrioxamine B (DFO) (Lytton et al., Mol. Pharmacol. 40, 584, 1991). Modification of DFO at its terminal amine renders it more lipophilic, imparts to i