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Iron(III)-Catalyzed and Air-Mediated Tandem Reaction of Aldehydes, Alkynes and Amines: An Efficient Approach to Substituted Quinolines

✍ Scribed by Ke Cao; Fu-Min Zhang; Yong-Qiang Tu; Xiao-Tao Zhuo; Chun-An Fan

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 156 KB
Volume: 15
Category: Article
ISSN: 0947-6539
DOI: 10.1002/chem.200900875

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✦ Synopsis

Abstract

Economic and practical advantages are offered by the iron(III)‐catalyzed and air‐mediated tandem coupling/hydroarylation/dehydrogenation of simple readily available aldehydes, alkynes, and amines for the synthesis of 2, 4‐disubstituted quinolines (see scheme).magnified image

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