Iron(II)-Catalyzed Asymmetric Hydrosilylation of Acetophenone

✍ Scribed by Michelle Flückiger; Antonio Togni

• Book ID: 102831433
• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: English
• Weight: 514 KB
• Volume: 2011
• Category: Article
• ISSN: 1434-193X
• DOI: 10.1002/ejoc.201100550

✦ Synopsis

Four new ligands containing a pentasubstituted cyclopentadiene tethered to a stereogenic diamine unit have been prepared and used in the iron-catalyzed enantioselective hydrosilylation of acetophenone. Catalytically active species have been generated in situ starting from various sources of iron. Fe(acac) 2 was the catalyst precursor of choice, whereas other simple Fe II or Fe III compounds resulted in significantly lower [a