## Abstract ## BACKGROUND: In 2007, the US Food and Drug Administration (FDA) issued regulatory alerts for use of erythropoiesisβstimulating agents (ESAs) in cancer patients with anemia after clinical trials and metaβanalysis data found that high ESA doses were associated with adverse outcomes in
Iron supplementation and erythropoiesis-stimulatory agents in the treatment of cancer anemia
β Scribed by Paolo Pedrazzoli; Giovanni Rosti; Simona Secondino; Salvatore Siena
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 102 KB
- Volume
- 115
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Safety concerns surrounding the use of recombinant human erythropoietin (Epo) to treat anemia in cancer patients were raised after 2 recent clinical studies reported a worse survival outcome in patients who received epoetin Ξ± or epoetin Ξ² compared with patients who received placebo. Alt
## Abstract Patients with cancer develop serious bacterial infections often, especially during periods of severe and prolonged neutropenia. Antibiotic usage for the prevention and treatment of bacterial infections in these highβrisk patients leads to selection pressures resulting in the emergence a
BACKGROUND. Although significant advances have been made in the treatment of some malignancies, the prognosis of patients with metastatic tumors remains poor. Differentiating agents redirect cells toward their normal phenotype and therefore may reverse or suppress evolving malignant lesions or preve