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Iron species of hepatic microsomes from control and phenobarbital-treated rats

โœ Scribed by Mark R. Montgomery; Connie Clark; Jordan L. Holtzman

Book ID
117042818
Publisher
Elsevier Science
Year
1974
Tongue
English
Weight
484 KB
Volume
160
Category
Article
ISSN
0003-9861

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A kinetic analysis of cytochrome P450mediated desulfuration (activation) or dearylation (detoxication) showed that rat hepatic microsomes have a greater capacity to detoxify and a lower capacity to activate chlorpyrifos compared to parathion. Kinetic curves for the desulfuration of both parathion an