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Iron oxide nanoparticles as magnetic resonance contrast agent for tumor imaging via folate receptor-targeted delivery1

✍ Scribed by Choi, Hoon; Choi, Seok Rye; Zhou, Rong; Kung, Hank F.; Chen, I.-Wei

Book ID
119998522
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
301 KB
Volume
11
Category
Article
ISSN
1076-6332

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## Abstract A new macromolecular gadolinium‐based magnetic resonance imaging (MRI) contrast agent, folic acid (FA)–poly(ethylene glycol) (PEG)–polyamidoamine dendrimer (PAMAM)–Gd, was synthesized with a core of PAMAM, which was modified with conjugates of FA and PEG and then chelated by gadolinium