Iron overload in myelodysplastic syndromes: A Canadian consensus guideline
β Scribed by Richard A. Wells; Brian Leber; Rena Buckstein; Jeffrey H. Lipton; Wanda Hasegawa; Kuljit Grewal; Karen Yee; Harold J. Olney; Loree Larratt; Linda Vickars; Alan Tinmouth
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 377 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0145-2126
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π SIMILAR VOLUMES
Anaemia is prevalent in patients with myelodysplastic syndromes (MDS), and most patients with MDS receive regular red blood cell transfusions, which can lead to iron overload. Some patients may already have iron overload before transfusions begin, as a result of ineffective erythropoiesis. Iron over
Many patients with myelodysplastic syndromes (MDS) have severe anaemia. However, regular blood transfusions, which are widely used to maintain quality of life and prevent anaemia-related morbidity and mortality, have a negative impact on survival as a result of iron overload. Retrospective surveys h
## Abstract ## BACKGROUND Approximately 15,000 new cases of myelodysplastic syndromes (MDS) are expected in the United States each year. ## METHODS The mainstay for the management of myelodysplastic syndromes (MDS) is supportive therapy with red blood cell (RBC) transfusions to improve the patie