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Iron kinetics: Modelling and parameter estimation in normal and anemic states

✍ Scribed by C. Berzuini; P.Colli Franzone; M. Stefanelli; C. Viganotti

Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
979 KB
Volume
11
Category
Article
ISSN
0010-4809

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✦ Synopsis

A seven-compartment model for ferrokinetics is presented here and an optimization algorithm of the gradient type for the evaluation of its parameters is described. The reliability of the parameter estimates is tested calculating marginal standard deviations by computing the information matrix through the sensitivity coefficients. The reality and clinical implications of the model are discussed and the values of its parameters in normal and anemic states speculated upon.

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