Iron is not involved in oxidative stress-mediated cytotoxicity of doxorubicin and bleomycin
✍ Scribed by H Kaiserová; G J M den Hartog; T Šimůnek; L Schröterová; E Kvasničková; A Bast
- Book ID
- 110009318
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 256 KB
- Volume
- 149
- Category
- Article
- ISSN
- 0007-1188
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Oxygen is essential for aerobic life, although reactive oxygen intermediates can be highly toxic to cells. Superoxide radicals and hydrogen peroxide become particularly harmful __in vivo__ due to their reactivity with transition metals like iron, producing hydroxyl radicals, which are involved in DN
The activation of protein tyrosine kinase(s) (PTK) is a critical event required for the development of NK cell-mediated cytotoxicity. Here we demonstrate that the adaptor protein shc undergoes tyrosine phosphorylation during the generation of antibody-dependent cellular cytotoxicity (ADCC) and natur