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Iron induction of ferritin synthesis and secretion in a human hepatoblastoma cellline (HepG2)

✍ Scribed by Lescoat, G.; Moirand, R.; Hubert, N.; Dezier, J.F.; Pasdeloup, N.; Deugnier, Y.; Brissot, P.


Book ID
122937081
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
57 KB
Volume
9
Category
Article
ISSN
0168-8278

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The uptake of radiocopper by HepGZ cells is a saturable, temperature-dependent and cellular energy-independent process with a V,, of 7.1 f 0.2 pmoles min-' mg protein-' and an estimated K, of 3.3 f 0.5 wM. The rate of copper uptake is reduced at an equimolar concentration of albumin and is unaffecte