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Iron-catalyzed tandem reactions of aldehydes, terminal alkynes, and primary amines as a strategy for the synthesis of quinoline derivatives

✍ Scribed by Yicheng Zhang; Pinhua Li; Lei Wang

Publisher
Journal of Heterocyclic Chemistry
Year
2010
Tongue
English
Weight
86 KB
Volume
48
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

FeCl~3~‐catalyzed three‐component tandem condensation/addition/cyclization/oxidation reactions of aldehydes, terminal alkynes, and primary amines have been developed. The processes can provide a diverse range of quinoline derivatives in good yields from simple starting materials. A possible reaction mechanism was proposed. J. Heterocyclic Chem., (2010).

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