Iron-Catalyzed Halogenation of Alkanes: Modeling of Nonheme Halogenases by Experiment and DFT Calculations

Modeling the Photochemistry of the Refer

Modeling the Photochemistry of the Reference Phototoxic Drug Lomefloxacin by Steady-State and Time-Resolved Experiments, and DFT and Post-HF Calculations

✍ Mauro Freccero; Elisa Fasani; Mariella Mella; Ilse Manet; Sandra Monti; Angelo A 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 635 KB

## Abstract The irradiation in water of 1‐ethyl‐6,8‐difluoro‐7(3‐methylpiperazino)3‐quinolone‐2‐carboxylic acid (lomefloxacin), a bactericidal agent whose use is limited by its serious phototoxicity (and photomutagenicity in the mouse), leads to formation of the aryl cation in position eight that i